Health Care Providers

Vonacor Prescribing Information: 
 
Product Description:
Microactive Curcumin™ Proprietary Blend 500 mg *
Turmeric root extract (Curcuma Longa) (Standardized with 25% curcuminoids),
polyglycerol oleate, HPMC, Silica, medium chain triglycerides, sodium alginate.

Indications and usage:
Promotes a Balanced Inflammatory Response.
Optimal Joint Health Support.

Dosing and Administration:
Indicated for patients 12 years and older. The starting dose for Vonacor is one capsule per day, which can be increased to either two capsules per day or one capsule twice daily.
Vonacor can be taken with or without food, its absorption can be enhanced when taken alongside a meal, particularly one that includes healthy fats.

Time required to achieve effectiveness:
The length of time required for curcumin to take effect can vary depending on several factors, such as the individual's health status, the dosage, and the condition being treated. While some people may experience the benefits of curcumin within a few days, others may need to use it regularly for several weeks or even months to see significant results.

For instance, curcumin supplements have been shown to help alleviate inflammation and joint pain in individuals with osteoarthritis, with some studies indicating that it may take up to eight weeks of consistent use to experience improvements. Similarly, curcumin may aid in cognitive function in individuals with mild cognitive impairment, but several months of regular use may be necessary to see positive changes.

It's worth noting that the effects of curcumin may be more pronounced when combined with other lifestyle modifications, including a healthy diet, regular exercise, and stress management techniques. If you're using curcumin supplements to address a specific medical condition, it's crucial to follow the advice of your healthcare provider and to exercise patience with the treatment. Additionally, it's always recommended to speak with your healthcare provider before starting a new supplement regimen.

Contraindications:
Curcumin is generally considered safe for most people when taken in recommended doses. However, there are some contraindications and precautions that should be considered before taking curcumin supplements, including:

1. Bleeding disorders: Curcumin may increase the risk of bleeding, particularly in individuals with bleeding disorders or those taking blood-thinning medications.
2. Gallbladder issues: Curcumin may stimulate the production of bile, which could worsen gallbladder problems.
3. Pregnancy and breastfeeding: There is not enough evidence to determine the safety of curcumin supplements during pregnancy and breastfeeding, so it is best to avoid them.
4. Surgery: Curcumin may increase the risk of bleeding during and after surgery, so it is recommended to stop taking curcumin at least 2 weeks before any scheduled surgery.

5. Allergies: Individuals with allergies to turmeric or yellow food dyes should avoid curcumin supplements.
6. Iron deficiency: Curcumin may interfere with the absorption of iron, so individuals with iron deficiency should use caution when taking curcumin supplements.

Warnings and Precautions:
1. Interactions with medications: Curcumin supplements may interact with certain medications, including blood thinners, chemotherapy drugs, and medications for diabetes. If you are taking any medication, it is important to talk to your doctor before taking curcumin supplements.
2. Allergic reactions: Some people may be allergic to curcumin or turmeric. If you experience any allergic symptoms, such as hives, swelling, or difficulty breathing, stop taking curcumin immediately and seek medical attention
3. Pregnancy and breastfeeding: There is not enough research to determine if curcumin is safe during pregnancy and breastfeeding. Therefore, it is best to avoid using curcumin supplements during these times.
4. Digestive issues: Some people may experience digestive issues, such as diarrhea or nausea, when taking curcumin supplements. If you experience these symptoms, stop taking curcumin and speak to your doctor.
5. Dosage: It is important to follow the recommended dosage on the supplement label or as directed by your healthcare provider. Taking too much curcumin can cause side effects, including stomach upset and diarrhea.

Adverse Reactions:
1. Gastrointestinal Issues: Some people may experience gastrointestinal issues, such as nausea, diarrhea, bloating, and abdominal pain, when taking curcumin supplements.
2. Allergic Reactions: In rare cases, curcumin may cause allergic reactions, such as hives, rash, itching, and difficulty breathing.
3. Bleeding: Curcumin may have blood-thinning properties, which can increase the risk of bleeding, especially if taken in high doses or with blood-thinning medications.
4. Gallbladder Issues: Curcumin may increase the production of bile, which can exacerbate gallbladder problems, such as gallstones or biliary colic.
5. Interactions with Medications: Curcumin may interact with certain medications, such as blood-thinners, antiplatelet drugs, and chemotherapy medications. It is important to talk to a healthcare provider before taking curcumin supplements if you are on any medications.
6. Liver Toxicity: Some studies suggest that curcumin may cause liver toxicity in rare cases, especially when taken in high doses or for long periods.
7. Low Blood Sugar: Curcumin may lower blood sugar levels, which can be problematic for people with diabetes who are already taking medications to lower their blood sugar levels. If you experience any adverse reactions while taking curcumin, it is important to stop taking it and consult with your healthcare provider.

Drug Interactions:

Curcumin supplements may interact with certain medications, which can affect their efficacy or cause adverse reactions. The following are some of the known drug interactions associated with curcumin:

1. Blood thinners: Curcumin may have blood-thinning properties, which can increase the risk of bleeding when taken with anticoagulant medications, such as warfarin, heparin, and aspirin.
2. Antiplatelet drugs: Curcumin may also increase the risk of bleeding when taken with antiplatelet medications, such as clopidogrel and ticlopidine.
3. Chemotherapy drugs: Curcumin may interfere with the efficacy of chemotherapy medications, such as doxorubicin and cyclophosphamide, by reducing their bioavailability.
4. Diabetes medications: Curcumin may lower blood sugar levels, which can be problematic for people with diabetes who are already taking medications to lower their blood sugar levels, such as insulin and sulfonylureas.
5. Statins: Curcumin may interfere with the efficacy of statin medications, which are used to lower cholesterol levels, by reducing their bioavailability.
6. Immunosuppressant drugs: Curcumin may interfere with the efficacy of immunosuppressant medications, such as cyclosporine and tacrolimus, by reducing their bioavailability.
7. Nonsteroidal anti-inflammatory drugs (NSAIDs): Curcumin may enhance the anti-inflammatory effects of NSAIDs, such as ibuprofen and aspirin, which can increase the risk of bleeding and gastrointestinal side effects.

Overdosage:
Curcumin is generally considered safe when used in recommended dosages. However, taking high doses of curcumin supplements can cause adverse reactions. The following are some of the potential symptoms of curcumin overdose:
1. Gastrointestinal Issues: High doses of curcumin supplements may cause gastrointestinal issues, such as nausea, vomiting, diarrhea, and abdominal pain.
2. Bleeding: Curcumin supplements may have blood-thinning properties, which can increase the risk of bleeding when taken in high doses.
3. Liver Toxicity: Some studies suggest that high doses of curcumin supplements may cause liver toxicity in rare cases.
4. Hypoglycemia: High doses of curcumin supplements may lower blood sugar levels, which can be problematic for people with diabetes.

Patient Counseling Information:
1. Dosage: Follow the recommended dosage guidelines on the supplement label and do not exceed the recommended dosage.
2. Adverse reactions: Be aware of the potential adverse reactions associated with curcumin supplements, such as gastrointestinal issues, allergic reactions, bleeding, gallbladder issues, interactions with medications, liver toxicity, and low blood sugar.
3. Drug interactions: Discuss with patients all the medications they are taking, including over-the-counter drugs, supplements, and herbal remedies, to avoid drug interactions.
4. Pregnancy and breastfeeding: Curcumin supplements are not recommended for use during pregnancy or breastfeeding due to the lack of safety data.
5. Surgery: Prior to surgery, it is important to advise patients scheduled for the procedure that taking curcumin supplements could potentially heighten the risk of bleeding.

Storage:
Store curcumin supplements in a cool, dry place away from direct sunlight and out of reach of children.

Fortinex Prescribing Information:

Product Description:

Each capsule contains:
Vitamin D3 – 62.5 mcg
Vitamin K2 – 100 mcg
Vitamin C – 50 mg
Vitamin E – 15 IU (10 mg)
goMCT (Medium Chain Triglycerides) – 40mg
Resveratrol – 30 mg
NADH – 10 mg
CoQ10 – 10 mg

Indications and Usage:

Fortinex is a comprehensive formula that combines essential nutrients for bone metabolism, spine health, and cellular function. Vitamin D3 supports bone health, immune system function, , while Vitamin K2 helps with calcium metabolism and bone health. Vitamin C and Vitamin E provide antioxidant protection. goMCT supports energy metabolism, Resveratrol provides antioxidant benefits, NADH supports cellular energy production, and CoQ10 promotes heart health and energy production.

Dosing and Administration:

As a dietary supplement, take one capsule daily preferably with a meal or an 8 oz glass of water, or as directed by a healthcare professional.

Contraindications:

Fortinex is contraindicated in individuals with:
Known hypersensitivity to any of the ingredients.
Hypercalcemia (high levels of calcium in the blood).
Severe liver or kidney disease.

Warnings and Precautions:

Pregnancy and Lactation: Consult a healthcare provider before use if you are pregnant, nursing, or planning to become pregnant.
Medical Conditions: Individuals with bleeding disorders or those taking anticoagulant or antiplatelet medications should use this product with caution and under medical supervision due to the presence of Vitamin K2 and other components that can affect blood clotting.
Surgery: Discontinue use at least two weeks prior to elective surgery due to the potential for increased bleeding risk.
Kidney Disease: People with kidney disease should consult their healthcare provider before taking this supplement.
Hypercalcemia: People with hypercalcemia should avoid Vitamin D3 supplements or only take them under the supervision of a healthcare provider.
   
Adverse Reactions:

While adverse reactions are generally rare, the following may occur:
Gastrointestinal: Nausea, diarrhea, stomach cramps.
Allergic Reactions: Rash, itching, swelling, dizziness, trouble breathing.
Other: Headache, fatigue.

Drug Interactions:

Blood Thinners: Vitamin K2 can interfere with the effectiveness of blood-thinning medications, such as warfarin. Consult your healthcare professional before taking this supplement if you are taking blood thinners.
Antacids: Antacids can decrease the absorption of Vitamin D3. Consider taking this supplement at a different time of day to avoid interfering with the absorption of Vitamin D3.
Statins: CoQ10 may interact with statins or other cholesterol-lowering medications, potentially altering their effectiveness.

Overdosage:

In case of accidental overdose, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, diarrhea, and increased bleeding tendency.
Vitamin D3: Overdosing can lead to hypercalcemia, with symptoms such as nausea, vomiting, weakness, and confusion. Long-term hypercalcemia can cause kidney damage and bone loss.
Vitamin K2: While there is no known toxicity for Vitamin K2, taking very high doses could interfere with blood-thinning medications, leading to an increased risk of blood clots.
CoQ10: High doses can cause gastrointestinal upset, including nausea and diarrhea.

Patient Counseling Information:

Vitamin D3: Essential for strong bones and teeth, proper immune function, and maintaining healthy calcium and phosphorus levels. Monitor for signs of toxicity, such as nausea and constipation.
Vitamin K2: Crucial for blood clotting and bone health. Monitor for signs of deficiency, such as easy bruising and bleeding.
Vitamin C and Vitamin E: Provide antioxidant protection. Monitor for gastrointestinal upset.
goMCT: Supports energy metabolism. No known significant side effects.
Resveratrol: Provides antioxidant benefits. Monitor for potential gastrointestinal discomfort.
NADH: Supports cellular energy production. No known significant side effects.
CoQ10: Promotes heart health and energy production. Monitor for gastrointestinal upset.

Storage:

Store in a cool, dry place. Keep out of reach of children.

Vonaflex Prescribing Information:

Product Description:
Ingredients Lidocaine 4%, Arnica Montana flower extract, cetearyl, alcohol, cetyl ester waxes, cyclopentasiloxane, disodium EDTA, ethoxydiglyciol, Heliantus annuus (sunflower oil), Lavanvula Angustifolia (lavender oil), methylparaben, PEG040 hydrogenated caster oil, poly (acrylic acid) 2-propionic acid homopolymer, propylene glycol, propylparaben, tetrahydrocurcumin, tocopherol acetate, triethanolamine, water.

Indications and usage:
Vonaflex is indicated for the temporary relief of pain associated with:
• Arthritis
• Backache
• Sprains
• Strains
• Bruises
• Muscle and joint pain
• Minor skin irritations

Dosing and Administration:
Adults and children 12 years and older: Apply a thin layer to the affected area no more than 3 or 4 times a day (or no more than 8 pump plunges per day). Rub in for 15 to 20 seconds.
Do not exceed the recommended dose or frequency of use.
Wash hands before and after use.

Time required to achieve effectiveness:
Vonaflex lotion typically takes about 15-30 minutes to start working and provides local anesthesia and pain relief. The maximum effect of Vonaflex is usually reached within 60-90 minutes after application.
It is important to follow the instructions on the label regarding the dosage and frequency of application for optimal effectiveness.

Contraindications:
1. Hypersensitivity to any of the ingredients in the ointment.
2. Allergy to lidocaine or any other local anesthetic: If you have had an allergic reaction to lidocaine or any other local anesthetic in the past, you should avoid using lidocaine ointment.
3. Skin infections or open wounds: Do not apply lidocaine ointment to any area of the skin that is infected or has an open wound. This can increase the risk of the infection spreading or causing further damage.
4. Liver disease: Lidocaine is metabolized in the liver, so people with liver disease may have difficulty metabolizing the drug properly. This can lead to a buildup of lidocaine in the body and increase the risk of adverse effects.
5. Heart problems: Lidocaine can affect the heart rhythm, so people with heart problems should use caution when using lidocaine ointment. This includes people with a history of heart attack, heart failure, or arrhythmias.
6. Pregnancy and breastfeeding: Lidocaine ointment should be used with caution during pregnancy and breastfeeding. There is limited research on the safety of lidocaine during these times, so it is best to consult with a healthcare provider before using it.

Warnings and Precautions:
Vonaflex is a local anesthetic that is used to relieve pain and discomfort associated with a variety of conditions. While it is generally considered safe, there are some warnings and precautions that you should be aware of before using it. 

These include:
1. Allergy: If you are allergic to lidocaine or any other local anesthetic, you should not use Vonaflex.
2. Medical history: Inform your doctor if you have any medical conditions or if you are pregnant or breastfeeding. Vonaflex may not be safe for everyone, and your doctor will be able to determine if it is right for you.
3. Interaction with other drugs: If you are taking any other medications, including prescription and over-the-counter drugs, inform your doctor before using Vonaflex. It can interact with other drugs and cause serious side effects.
4. Application: Vonaflex should be applied only as directed. Do not apply more than the recommended dose, and do not apply it to broken or irritated skin.
5. Side effects: Some common side effects of Vonaflex include redness, swelling, and itching at the application site. If you experience any other side effects, such as difficulty breathing or a rapid heartbeat, seek medical attention immediately.

Adverse Reactions:
Vonaflex is a combination of lidocaine ointment, arnica oil, and curcumin. Adverse reactions can vary depending on the individual's sensitivity and allergic response.
1. Lidocaine ointment is a local anesthetic used to numb the skin or mucous membranes. Some possible adverse reactions to lidocaine ointment include skin irritation, redness, itching, rash, and swelling. In rare cases, lidocaine can cause an allergic reaction, which can lead to symptoms such as difficulty breathing, swelling of the face or throat, and anaphylaxis.
2. Arnica oil is a natural remedy used to relieve pain and swelling. However, some people may be allergic to arnica oil, and adverse reactions may include skin irritation, redness, itching, rash, and swelling. 
3. Curcumin is an ingredient in turmeric that has anti-inflammatory and antioxidant properties. Adverse reactions to curcumin are rare but can include stomach upset, nausea, and diarrhea. Some people may also be allergic to curcumin, which can lead to symptoms such as hives, itching, and difficulty breathing.

Drug Interactions:
Overall, there are no significant drug interactions when using lidocaine ointment, arnica oil, and curcumin together topically. However, if you are taking any medications, it is important to consult with your healthcare provider before using these substances to avoid potential interactions.

Overdosage:
1. In the case of lidocaine ointment, an overdose may cause symptoms such as seizures, confusion, blurred vision, ringing in the ears, or slowed breathing. If an overdose is suspected, it is important to seek medical attention immediately.
2. Arnica oil and curcumin ointment are generally considered safe when used as directed. However, an overdose may cause skin irritation, redness, or itching. In rare cases, an allergic reaction may occur, which may result in difficulty breathing, swelling of the face, lips, tongue or throat. If an overdose is suspected, it is important to wash the affected area with soap and water and seek medical attention if symptoms persist or worsen. It is important to always use medications and topical treatments as directed and to never exceed recommended doses. If you have any concerns about the use of these or any other medications, you should speak with your healthcare provider or pharmacist.

Patient Counseling Information:
1. Use as directed: Follow the instructions provided by your healthcare provider and the instructions on the label. Do not apply more than recommended.
2. Skin irritation: May cause skin irritation, redness, or itching. If you experience any of these symptoms, stop using the ointment and contact your healthcare provider.
3. Allergic reactions: Allergic reactions are rare, but if you develop a rash, hives, difficulty breathing, or swelling of the face or tongue, seek medical attention immediately. Avoid contact with eyes and mouth: Should not come in contact with your eyes or mouth. If it accidentally gets in your eyes, rinse thoroughly with distilled water.
4. Keep out of reach of children: Store out of reach of children and pets.

Storage:
Vonaflex should be stored in a cool, dry place, away from direct sunlight and heat.

Optinexx Prescribing Information:
 
Product Description:

Optinexx is a dietary supplement formulated to provide essential nutrients for overall health and wellness. Each capsule contains vegan omega-3, Vitamin E, Olive Fruit Oil, and Hesperidin.

Indications and usage:

Optinexx is indicated for use as a dietary supplement to support optimal joint and heart health. It provides essential fatty acids, antioxidants, and flavonoids to promote joint and cardiovascular function.

Dosing and Administration:

Adults: Take one capsule daily with a meal or an 8 oz glass of water, or as recommended by a physician.

Contraindications:

Optinexx is contraindicated in individuals with: 
Known hypersensitivity to any of the ingredients. 
Hypervitaminosis E (an excess of Vitamin E in the body).

Warnings & Precautions:

Pregnancy and Lactation: Consult a healthcare provider before use if you are pregnant, nursing, or planning to become pregnant to get proper guidance.
Medical Conditions: Individuals with bleeding disorders or those taking anticoagulant or antiplatelet medications should use this product with caution and under medical supervision due to the presence of Vitamin E and Omega-3 fatty acids, which can affect blood clotting.
Surgery: Discontinue use at least two weeks prior to elective surgery due to the potential for increased bleeding risk.
Allergic Reactions: Discontinue use and consult a healthcare provider if any adverse reactions occur, such as rash, itching, swelling, dizziness, or trouble breathing.

Adverse Reactions: 

While adverse reactions are generally rare, the following may occur:
Gastrointestinal: Nausea, diarrhea, stomach cramps.
Allergic Reactions: Rash, itching, swelling, dizziness, trouble breathing.
Other: Headache, fatigue.

Drug interactions:

Anticoagulants/Antiplatelet Drugs: Increased risk of bleeding due to the combination of Omega-3 and Vitamin E.
Blood Pressure Medications: Omega-3 fatty acids may lower blood pressure, which can be additive with blood pressure-lowering medications.
Vitamin E Supplements: Avoid concurrent use of additional Vitamin E supplements to prevent excessive intake and potential toxicity.

Overdose: 

In case of accidental overdose, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, diarrhea, and increased bleeding tendency.

Storage & Handling:

Store at room temperature, 20-25°C (68-77°F).
Protect from light and moisture.
Keep out of reach of children.